Projects

I promised at the beginning of class that you would do original research as part of a "project." I am going to deliver on that promise on the last day of class. But don't worry, your project will take between 5 and 15 minutes and then you can enjoy your summer. And grades for the class will be only based on homework: the last-day-of-class project will be a 10 point homework like the others.

Question

What does the likelihood function look like for Hodgkin-Huxley (current based) models. Does it look like the LS-cost function or the UG-cost function. Few, if any, people, besides me, have looked at this, and I have done woefully few numerical experiments. I don't know and I don't think anyone else does either, but we are going to find out.

This is how it is going to work. You are going to program the computer to plot a likelihood function. This will be easy. You are going to download then edit one of three key files. Each key file correspond to a different model.

• The Hodgkin-Huxley model

• A single compartment, many-current, model of the LP cell in the lobster stomatogastric ganglion.

• The two compartment Ghostburster model.

The first model was written by me, the other two were written by students in this class as an extra (non-credit) project.