Syllabus

• NIA2 Introductory Tutorial

• NIA2 Membrane Tutorial

• NIA2 Equilibrium Potential Tutorial

• NIA2 Sodium Action Potential Tutorial

• NIA2 Voltage Clamping a Patch Tutorial

• Differential equations and basic concepts of numerical analysis of differential equations. Discretizing a continuous model (RC-circuit) with Euler's method. A Matlab primer.

• Identifying an RC-circuit with time domain methods and an injected current. Two cell network of RC circuits with linear graded synapse. Phase plane analysis. Parameter estimation when model structure is wrong.

• Multiple compartment modeling with active conductance. The model structures we will use for projects.

• Maximum likelihood estimation, part I

• Maximum likelihood estimation, part II

• Maximum likelihood estimation, part III

• Bayesian filtering and using my fitting software: PROJECT PROPOSAL ASSIGNED.

• NIA2 The Passive Axon Tutorial

• NIA2 The Unmyelinated Axon: PROJECT PROPOSALS DUE

• NIA2 Sodium and Potassium Channel Kinetics Tutorial

• NIA2 Axon Diameter Change

• NIA2 Nonuniform Channel Densities

• NEURON Programming (Several classes -- to be decided)

• More NIA2 Tutorials (Several classes -- to be decided)